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Dutasteride: The Truth and the Fiction
Although a prostate treatment may sound like a strange choice for treating hair loss, in fact Dutasteride is one of the top choices of medication for those who are losing their hair. Although this drug has not yet been approved as a hair loss treatment in Europe or the United States, it has already been given approval in South Korea and Japan. While it has been shown to be effective, there are some downsides to its use that may put some people off using it.
How Does Dutasteride Work?
Men who have pattern baldness have high dihydrotestosterone levels – a hormone which is made by an enzyme called 5-alpha reductase from the body’s natural testosterone. Dutasteride works by stopping the 5-alpha reductase enzyme and blocking the dihydrotestosterone from forming. This helps to prevent the hair loss that is associated with high levels of the hormone. It increases the amount of hairs in the scalp, thus filling in any thin areas. While Dutasteride will have different results for each person, usually its users will never re-grow all of the hair that they lost.
How Well Does It Work?
Recent studies have shown that Dutasteride can be more effective when it comes to hair regrowth than other oral medications. Patients who take the 0.5 mg pill have reported fuller and thicker hair, however other users have reported some worrying side effects. Still others found that the pills had no effect at all, with no extra hair growth experienced.
Side effects are quite common with this type of treatment since the inhibition of 5-alpha reductase does not only reduce the hormone levels in the scalp, in also reduces its levels elsewhere in the body too. Dutasteride is a strong medication and can therefore reduce dihydrotestosterone by as much as 95%, and this explains why, although some of the side effects were quite minor, there were some other more serious effects including:
- Reduced libido
- Impotence
- Irregular ejaculation
- Reduced sperm count
- Low testosterone levels
- Increased risk of prostate cancer
Dutasteride Mesotherapy Treatment Benefits
One potential alternative to oral Dutasteride is a mesotherapy scalp injection treatment which injects the Dutasteride directly into the affected area. One of the advantages of this treatment appears to be that the hormone levels are limited solely to the scalp without any side effects being experienced, and initial findings appear to be quite positive as to the efficacy of the results.
While some men who are extremely distressed by their hair loss may be happy to risk the potential side effects of taking Dutasteride in an attempt to slow down or halt the problem, many others would rather try a less risky treatment. An instant hair thickener is one possible alternative with no unwanted side effects which can restore the effect of a thicker and fuller head of hair. Quick and easy to apply, it is one of the easiest and most convenient ways to help boost confidence and improve appearance.
Studies Point to New Use of Modified Protein to Fight Against Hair Loss
If you have not yet heard of either ‘FOXO4-DRI’ or ‘senescent cells’ we would not be surprised as these two terms have not been used as part of the discussion on hair loss until very recently. For many years, the technology and medicine involved with treating hair loss has been at a bit of a standstill, with no big medical revelations having occurred for a very long time. The same treatment options that are in use today have been around for decades. There have indeed been advancements in the effectiveness of those treatments, but when it comes to ground-breaking new methods and new ways of approaching treatment options, there has been little progress.
The fact that new technology and scientific knowledge connected to the topic of hair loss is a bit slow-coming, means it is always very exciting when we hear of a promising new study, and that is exactly what this article is about. A large, multi-faceted scientific project has been underway involving scientists and researchers from many countries. The study has been a central work of several universities, and was funded by a range of interested parties. This team of scientists has uncovered an amazing new technique that has been found to remove inactive aged cells which effectively reduces and reverses the ageing process, which in turn helps treat hair loss.
Before you get too excited about this study it should be said that the work is currently only being carried out on lab mice, but the results seem to be very promising. Hair loss isn’t the only positive from this new modified protein either. It has been found that the inclusion of the protein to areas suffering from tremendous stress – such as cell areas affected by radiation treatment – was largely unaffected by the stress. This could point to many different types of hair loss treatments in the future and these could be varied enough to be effective no matter what the cause of the thinning hair turns out to be.
If the cause of hair loss is genetic, the research shows that these proteins may actually be able to do two things. One is that they can revitalize the aged areas of the scalp that have been negatively impacted by the metabolite dihydrotestosterone, known as DHT, that builds up and kills off the hair follicles. Another is that the modified proteins might actually help stop all future communication between the cells that ‘don’t agree’ making the solution permanent, which is something that current products cannot yet provide.
If the cause is more lifestyle-dependent, the possibilities of what these modified proteins can provide seems almost endless. If the proteins can be introduced to areas that have seen stress, but are not likely to see that same stress in the future, damage that has always been viewed as permanent may be seen as a curable condition in the very near future. The same goes for dietary issues. Once the diet has been modified to promote healthy hair growth, the affected areas can be treated for a near permanent solution.
While these are just theories at the moment, it is nice to think that our great minds are getting closer to a cure for baldness. It has been a difficult subject for people everywhere, and finding a cure would mean the world to so many of them.
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Frightening New Information on Finasteride
Sometimes in life, we are faced with very difficult decisions that have the potential to alter our lives in irreversible ways. If you are one of the millions of men or women who has begun to think about, or has already begun, a hair loss treatment plan, it is likely that you know just how difficult it can be to choose the best and most trusted method of saving your hair. As with almost everything in life, hair loss treatments come with a bit of risk which balances out the potential benefits. Choosing the one that is best for you, therefore, greatly depends on how those risks and benefits appear to you. One of the most talked-about hair loss drugs lately is the repurposed prostate drug called Finasteride. Better known by the brand name, Proscar, this drug has just had a new side effect listed on its label.
As a hair loss treatment, Finasteride is quite effective. There have been a few notable long-term studies that have cited almost 80% success rates in the men and women who took the medicine. That is a fairly respectable success rate for a medicine of this kind, so it is clear why it has become so popular among so many different types of people. The way Finasteride works is by inhibiting the DHT in the system. DHT is the primary cause of pattern baldness and by internally curbing the hormone, the condition also begins to go away. Finasteride has a few things in common with its cousin Rogaine which is that it goes after the DHT, but where it differs is that it is taken internally. Rogaine is a topical treatment comprised as a completely different drug, but the effects are very similar with both products. Finasteride take much longer to begin working as well, and that is mainly due to the fact the treatment is taken in tablet form.
Finasteride produces results, that much is clear, but what is also clear is that there are some side effects that anyone interested in this drug should know about. The most commonly complained about side effects are related to sexual function. In fact, the reports and complaints came in so strongly that an in-depth analysis and further study was ordered by the Food and Drug Administration (FDA) in the USA back in 2010 to understand the connection between the sexual side effects people were experiencing and the medicine itself. The result of the study was that up to 15% of men suffered some form of sexual discomfort and/ or dysfunction and the results prompted the FDA to oblige any company selling the drug to list sexual side effects on the label. Some of the most common side effects cited were reduced sex drive, erectile dysfunction, and reduced semen discharge.
There have been other side effects listed for this drug as well. People have reported feeling dizzy, weak, and faint when taking the medicine, and there have been problems with rashes, swollen scalp tissue, and headaches too. As with all medications, there is no guarantee that any given person will experience any of the side effects, but it is always good to know what is possible before starting a treatment plan. If you are thinking that the benefits can outweigh the risks for you, have a talk with your doctor so that you can get the best advice possible before you begin.
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The truth about testosterone and hair loss
Hair loss is an extremely common problem for both men and women and it can be very troubling when experienced first-hand, especially if you aren’t prepared or expecting it to happen. With hair loss an issue in around 40% of men in their mid-thirties, it is important to know that you are not alone when it comes to hair loss. Of course, hair loss is also a serious issue for women but in this piece we are mainly focusing on male hair loss and the role of testosterone.
Those suffering from hair loss often look to find the primary reasons behind it, but there is a lot of mis-information around concerning why and how hair loss occurs. With hair loss being something that around 80% of men will eventually encounter, even 40% of women by the age of 40 will suffer from thinning hair, it is important to get the facts straight.
Causes of Hair Loss
There are a number of reasons why hair loss occurs and in some instances the effects aren’t always permanent. Certain cases of Alopecia, along with instances of Anagen Effluvium and Telogen Effluvium, are generally considered to only be a temporary cause of hair loss, with hair able to grow back normally in a period of months.
Male pattern baldness however, is a hereditary condition that is present in a large number of men. This permanent condition will eventually lead to significant hair thinning and a receding hair line. In some cases this can eventually lead to complete baldness. With the majority of cases of hair loss being caused by male pattern baldness, this is where most of the misconceptions lie and the truth about testosterone’s role becomes murky.
The Role of Testosterone
One of the biggest myths about hair loss is that it is the direct result of testosterone levels, a myth that many use to explain why women don’t suffer from hair loss to the same extent as men do. Men and women both contain varying levels of the testosterone hormone along with the oestrogen hormone. While testosterone is a factor in hair loss, the testosterone levels in your body aren’t the defining reason why hair loss may be becoming a problem, but they do play an important role.
It is not testosterone itself that can cause hair loss, but a molecule produced by testosterone, known as dihydrotestosterone (DHT). DHT is produced when testosterone becomes synthesised with an enzyme called 5-alpha reductase, which is made naturally in the body. Over time, DHT makes hair follicles reduce in size, activating the thinning of hair until the follicles close completely and no more hair is able to grow.
DHT plays many important roles in the maintenance, protection and regulation of the human body, with hair loss being a potential negative result of its purpose. The process required to form DHT only happens with around 5% of the testosterone in the body. While this does mean that the higher the testosterone levels, the more chance that DHT will be produced, it is again, not a defining factor. Only people with a genetic predisposition to the negative effects of DHT will be prone to the effects of DHT production with the result of hair loss.
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Why Hair Loss in Young Men Is Increasing And How To Solve It
If we looked back just a decade ago, the lion’s share of males who had a receding hairline were middle-aged men. However, in recent years, boys as young as 16 are reported to be seeking advice following worries of a receding hairline. This is backed up by the fact that doctors in India have cited that hair loss among young men is steadily increasing.
This is not an issue that seems to be fading, and now the issue is so bad that male hair loss was the big topic of a workshop that 300 dermatologists from all over India sat in on. The people who are at the top of their game all sat and discussed treatments such as hair transplants, laser hair removal and anti-aging therapies, with many voicing concerns that Male Pattern Baldness is showing signs of advancing by at least a decade. Quite shocking, if you weren’t already aware, don’t you think?
Head of Dermatology at Ahmedabad Civil Hospital, Dr Bela Shah, spoke to the India Times at the time, saying: “Earlier, one would get patients showing signs of baldness in their late 30s or early 40s. Now, we get teenaged boys, some still attending school.”
So, what is at the root of the rise in hair loss among young men?
The scientific reasoning behind this issue is that hair starts to thin and the hairline recedes as a result of levels of dihydrotestosterone (DHT) rising. This hormone imbalance is down to genetics, so there’s not much you can do about that. However, it can be enhanced if you are under stress because this sends a message to the genes triggering hair loss to occur at a younger age.
Is there a way to overcome Male Pattern Baldness?
The increase in the volume of young men who are going through hair loss has caused many to suffer from anxiety and reduced levels of confidence and self-esteem as a knock-on effect. It has even been said to be ruining the chances at marriage for some. Subsequently, there has been an increase in interest of methods for overcoming the issues these men are suffering from.
One of the ways that a lot of males look to solve the problem is opting for hair transplant surgery. However, this can be an expensive solution, and thanks to today’s technology, there is a host of other techniques and products that can be used to help men deal with their loss of hair. For example, hair thickener products can do wonders, and this is an option that is perfectly discreet. This organic, coloured hair thickener can be sprayed directly onto the hair giving the user instant thickening!
How does this work?
Hair Thickener works by covering the scalp and hairs with a fine layer of liquid powder which bonds to the hair strands, thickening them. This results in the appearance of a thicker, fuller head of hair. What’s more, for those who do use the hair transplant route, once any scarring has healed hair thickener can be used to complement the end-product.
If you are one of the thousands of men who are silently continuing to live their lives unhappy with their appearance, then why not try a thickening spray and see what the results can do for you?
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